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Also, Li et al. have exposed the upregulation of PI3K/AKT pathway promotes the expressions of placental progress element (PlGF) and C-X-C Motif Chemokine Ligand one (CXCL1) in lung most cancers stem cells, which further more encourage angiogenesis [fifty nine]. CCPlenty of paracrine things secreted by MSCs are ligands for receptors that activate PI
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